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EV in reproduction

 ROOM 5

JE.I

THE EMERGING ROLE OF EXTRACELLULAR VESICLES IN REPRODUCTION:
FROM GAMETOGENESIS TO INTERACTION WITH IMMUNE SYSTEM

September 11

Chairs: Emily SCHIFANO, Sapienza University of Rome,  Annalisa RADEGHIERI & Alice GUALERZI, EVita and Luciana DINI, Sapienza University of Rome | GEI-SIBSC
In collaboration with
Sapienza tx Evita gei sibsc
Extracellular vesicles (EVs), that are produced from all cells that have been studied to date, are membrane- bound complexes secreted from cells under both physiological and pathological conditions. EV research is a rapidly evolving and expanding field, and it appears that all biological fluids contain very large numbers of EVs. EVs act as messengers for cell–cell communication and signalling due to their cargo, containing proteins, nucleic acids and lipids; recently they are also known to have roles in several reproductive processes. 
Although predominantly studied in mammals, extracellular vesicles are ubiquitous across metazoans. Research in non-mammalian models is critical for fully elucidating EV biology. Studies across diverse non-mammalian species reveal both highly conserved and uniquely adapted aspects of EV biology. From vertebrates to invertebrates, common themes emerge regarding EVs mediating immune regulation, tissue homeostasis, regeneration, and developmental signaling. Conserved EV biogenic pathways underlie EV release from Hydra to zebrafish. This workshop is aimed to discuss the role of EVs throughout reproduction (not only in humans), starting with the paternal and maternal gametes, followed by the establishment and continuation of successful pregnancies, with focus on the interaction of EVs with the maternal immune system and in various reproductive promotion and disorders. Additionally, we will explore how these concepts, well-documented in higher systems, are also relevant in less complex organisms, providing a broader understanding of EV function across different species.
 
September 11
09:00 - 10:30
Animal reproduction and the role of extracellular vesicles 1/2
JE.I.1 - TT.I.A
Chairs: Annalisa RADEGHIERI, EVita & Luciana DINI, Sapienza University of Rome | GEI-SIBSC
JE.I.1.1
TT.I.A.1
Danilo CIMADOMO - CV
Centro PMA Genera, Rome
Assisted Reproduction Technologies in a modern IVF lab: current practice and future challenges
!NEUTRO PPT eceded
JE.I.1.2
TT.I.A.2
Carlos SALOMON - CV
University of Queensland, Australia
Clinical Translation of Extracellular Vesicles in pregnancy: What Are We Missing?
!NEUTRO PPT eceded
JE.I.1.3
TT.I.A.3
Maurizio ZUCCOTTI - CV
University of Pavia
Cumulus cells release extracellular vesicles containing microRNAs their potential
!NEUTRO PPT eceded
 
11:30 - 13:00
Animal reproduction and the role of extracellular vesicles 2/2
JE.I.2 - TT.II.A
Chairs: Emily SCHIFANO, Sapienza University of Rome & Alice GUALERZI, EVita
JE.I.2.1
TT.II.A.1
Giulia FIORENTINO - CV
University of Pavia
Human cumulus cells-derived EVs and their role in the acquisition of the oocyte developmental competence
FIORENTINO Giulia PPT eceded
JE.I.2.2
TT.II.A.2
Paola VIGANÒ - CV
Polytechnic University of Milan
Embryo-derived EVs and their involvement  in implantation
!DONNA PPT eceded
JE.I.2.3
TT.II.A.3
Luciana DINI - CV
Sapienza University of Rome
Animal models for the study of EVs in reproduction
!UOMO PPT eceded
JE.I.2.4
TT.II.A.4
Emily SCHIFANO - CV
Sapienza University of Rome
Extracellular vesicles in Caenorhabditis elegans reproduction
!UOMO PPT eceded
 
14:00 - 15:30
Extracellular vesicles in reproduction - promotion and disorders
JE.I.3 - TT.III.L
Chairs: Emily SCHIFANO, Sapienza University of Rome | Annalisa RADEGHIERI & Alice GUALERZI, EVita | Luciana DINI, Sapienza University of Rome, GEI-SIBSC
JE.I.3.1
TT.III.L.1
Felipe VILELLA MITJANA - CV
INCLIVA Carlos Simon Foundation, Spain
Materno-Fetal Crosstalk. The First Lullaby
!DONNA PPT eceded
JE.I.3.2
TT.III.L.2
Stefania BIFFI - CV
IRCCS Burlo Garofolo
Extracellular vesicles as biomarkers in endometriosis and reproductive diseases
!DONNA PPT eceded
JE.I.3.3
TT.III.L.3
Fabrizio FONTANA - CV
University of Milan
Unraveling the role of extracellular vesicles in ovarian cancer stroma
!NEUTRO PPT eceded
JE.I.3.4
TT.III.L.4
Stefano TACCONI - CV
Carmen Laboratory, France
Lipotoxicity: a new role of lipid cargo in Extracellular Vesicles biology

!DONNA PPT eceded
 

 

 
    Go to Plan 11 September freccia DX f54
 

 

INFO & CONTACTS

Dr. Federica SCROFANI

Tel. +39 06 49766676
Mob. +39 339 7714107
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